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Antibiotic Indication Dose Timing 2 g po, *50 mg/kg po Amoxicillin Standard 1 hour earlier than If oral route cannot be 2 g im or iv, *50 mg im or iv Ampicillin ½ hour earlier than used Allergy to penicillin 600 mg po, *20 mg/kg 1 hour before Clindamycin Allergy to penicillin and 600 mg po or iv, *20 mg/kg iv ½ hour before oral route cannot be used Cephalexin or 2 g po, *50 mg/kg po Allergy to penicillin 1 hour earlier than cefadroxil Azithromycin 500 mg po, *15 mg/kg po 1 hour before or Allergy to penicillin clarithromycin Allergy to penicillin and 1g im or iv, *25 mg/kg Cefazolin ½ hour before oral route can't be used *pediatric dose; *po:oral route; **iv:intravenous route; *** im:intramuscular route. Differential Diagnosis Patients with coronary heart failure, chronic kidney disease, or decompensated liver disease might have bilateral edema of the lower extremities. 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